Detalhe da pesquisa
1.
Systematic discovery of mutation-directed neo-protein-protein interactions in cancer.
Cell
; 185(11): 1974-1985.e12, 2022 05 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-35512704
2.
Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease.
J Biol Chem
; 299(12): 105382, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37866628
3.
Nicardipine is a putative EED inhibitor and has high selectivity and potency against chemoresistant prostate cancer in preclinical models.
Br J Cancer
; 129(5): 884-894, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37474721
4.
Tumor microenvironment in a minipig model of spinal cord glioma.
J Transl Med
; 21(1): 667, 2023 09 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37752585
5.
Constitutively Synergistic Multiagent Drug Formulations Targeting MERTK, FLT3, and BCL-2 for Treatment of AML.
Pharm Res
; 40(9): 2133-2146, 2023 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-37704893
6.
Stress induces p38 MAPK-mediated phosphorylation and inhibition of Drosha-dependent cell survival.
Mol Cell
; 57(4): 721-734, 2015 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25699712
7.
Acquisition of taxane resistance by p53 inactivation in ovarian cancer cells.
Acta Pharmacol Sin
; 43(9): 2419-2428, 2022 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-35031699
8.
Discovery of the first chemical tools to regulate MKK3-mediated MYC activation in cancer.
Bioorg Med Chem
; 45: 116324, 2021 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34333394
9.
High expression of MKK3 is associated with worse clinical outcomes in African American breast cancer patients.
J Transl Med
; 18(1): 334, 2020 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32873298
10.
The OncoPPi Portal: an integrative resource to explore and prioritize protein-protein interactions for cancer target discovery.
Bioinformatics
; 34(7): 1183-1191, 2018 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29186335
11.
AKT1, LKB1, and YAP1 Revealed as MYC Interactors with NanoLuc-Based Protein-Fragment Complementation Assay.
Mol Pharmacol
; 91(4): 339-347, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28087810
12.
Akt and 14-3-3 control a PACS-2 homeostatic switch that integrates membrane traffic with TRAIL-induced apoptosis.
Mol Cell
; 34(4): 497-509, 2009 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-19481529
13.
Downregulation of urea transporter UT-A1 activity by 14-3-3 protein.
Am J Physiol Renal Physiol
; 309(1): F71-8, 2015 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25995111
14.
Chromosome instability in diffuse large B cell lymphomas is suppressed by activation of the noncanonical NF-κB pathway.
Int J Cancer
; 136(10): 2341-51, 2015 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25359525
15.
Small molecule antagonist reveals seizure-induced mediation of neuronal injury by prostaglandin E2 receptor subtype EP2.
Proc Natl Acad Sci U S A
; 109(8): 3149-54, 2012 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-22323596
16.
Reversing chemoresistance by small molecule inhibition of the translation initiation complex eIF4F.
Proc Natl Acad Sci U S A
; 108(3): 1046-51, 2011 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-21191102
17.
Discovery and structural characterization of a small molecule 14-3-3 protein-protein interaction inhibitor.
Proc Natl Acad Sci U S A
; 108(39): 16212-6, 2011 Sep 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-21908710
18.
Composition, characteristics, and treatment technologies of condensable particulate matter present in flue gas emitted by coking plants in China.
Sci Rep
; 14(1): 8522, 2024 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38609455
19.
Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM.
PLoS One
; 19(2): e0293548, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38359047
20.
Frequency-potency analysis of IgG+ memory B cells delineates neutralizing antibody responses at single-cell resolution.
Cell Rep
; 43(3): 113948, 2024 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38483908